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Question Answer
Why is it important for tetracycline to be stored in a cool, dark location?
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Exposure to heat and/or light causes it to decompose and become toxic.
What are special teaching instructions that should be shared with patients on tetracycline?
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Store is a cool, dark place. Wear sunscreen during periods of sun exposure.
What class of antibiotics can discolor the teeth of late term pregnant women and children under the age of 8?
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Tetracyclines, namely doxycycline.
Azithromycin peak levels may be reduced when taken concurrently with what type of medication?
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Antacids
__________ is an antibiotic that is known to reduce the effects of oral hypoglycemics.
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Levaquin
What class of medications can trigger CNS reactions including seizures if taken concurrently with Levaquin?
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NSAIDS
A drug that is a common substitute for penicillins (especially in the case of known allergy to penicillins) is?
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Erythromycin
Sore throat, purpura, decreased WBC & platelet counts are a sign of a hemtalogic reaction associated with what class of antibiotic medications?
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Sulfanomides
What are the major differences between Diflucan and Amphotericin B?
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Diflucan can only be administered orally, and Amphotericin B can only be administered via IV.
Drinking plenty of water while on sulfanomides prevents ___________.
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Crystalluria
Aminoglycosides are prescribed to treat infections with Gram ______ organisms.
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Negative
What class of medications are known to change the mechanism of action of Keflex?
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Uricosurics (like probenecid, benzbromarone and sulfinpyrazone)
What three classes of medications are contraindicated if a patient is on a macrolide?
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Acetaminophen, anticonvulsants, and anticoagulants. Macrolides include azithromycin and clarithromycin.
What adverse event is closely associated with quinolones like Levaquin?
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Stevens Johnson Syndrome
What specific electrolytes can be adversely impacted by Amphotericin B?
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Magnesium and Potassium (hypokalemia and hypomagnesemia)
What is the mechanism of action of fluoroquinolones?
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They inhibit bacterial synthesis of RNA and DNA
What are common side effects of tetracycline (3)?
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Photosensitivity, GI disturbances, and nephrotoxicity if given with other nephrotoxic drugs.
Levaquin should be used cautiously with ________ and __________ because it increases their effects.
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Caffeine and theophylline.
Amphotericin B is both bacteriostatic and bactericidal. It works by?
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Altering the membrane permeability which increases osmosis and causes cell lysis.


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