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Blood dyscrasias may occur as a result of high doses of _______ over a continuous period. Life threatening!
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sulfanomides
Amphotericin B is highly protein bound and therefore presents a risk for _______.
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nephrotoxicity
Taking acetaminophen with azithromycin increases the risk of _______.
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hepatotoxicity
Who should not take tetracycline's and why?
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1st trimester pregnant women: teratogenic effects. Children younger than 8, irreversibly stains teeth/same effect for women in 3rd trimester.
Most Cephalosporins are administered by the _______ and _______ routes.
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IM and IV
Tetracyclines increases the absorption of _______, which may lead to digitalis toxicity.
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Digoxin
What are signs and symptoms of super infections?
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Stomatitis (mouth ulcers), genital discharge (vaginitis), anal and genital itching.
Biaxin (clarithromycin) is considered a/an _______ macrolide.
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extended macrolide
The effects of _______ and _______ can be reduced when taken with tetracyclines.
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contraceptives and penicillins
Amphoteric B is classified as a _______ antifungal.
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polyenes
Tetracyclines should not be co-administered with _______ because of the increased risk of nephrotoxicity.
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aminoglycosides
To treat severe systemic fungal infections, the drug of choice is _______ in low doses, administered via _______.
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Amphotericin B by IV
Systemic fungal infections usually involve the _______ or _______.
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lungs or CNS
A contraindication for prophylactic treatment of tuberculosis is...
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alcoholism
Vitamin _______ is frequently given with isoniazid.
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B6-pyroxidine
What are the differences between 1st generation Cephalosporins and 4th generation ones?
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Each generation is effective against a broader spectrum of organisms. 4th generation are resistant to beta lactamases (1st aren't).
Cephalosporins have a _______ structure like _______.
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beta lactam structure like penicillins
Amoxicillin is a _______ spectrum drug.
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Broad
Mirthromax is considered a/an _______ macrolide.
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extended macrolide
The 1st and also current drug prescribed to treat tuberculosis is _______.
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streptomycin
Sulfanomide drugs are metabolized by the _______ and excreted by the _______.
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liver; kidneys
The new antibacterial drug that has a synergistic effect with sulfanomides is...
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trimethoprim
Food _______ absorption of Zithromax by 50%.
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decreases
_______ cross the blood brain barrier in children but not adults.
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Aminoglycosides
Serious adverse reactions to aminoglycosides include _______ and _______.
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nephrotoxicity; ototoxicity
It is necessary to draw peak and trough levels for Vancomycin to minimize _______ effects.
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toxic
The newest classification of antibiotic that is structurally related to macrolides is...
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ketolides
Vancomycin, aminoglycosides, and fluoroquinolones are _______ drugs.
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Bactericidal
Keflex is a _______.
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cephalosporin
Antacids and iron _______ absorption of Levaquin.
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decrease


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